Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

BE0001298ProteinAzotobacter vinelandii

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It is acted on by 3 drugs in DrugBank.

UniProtKB entry
P10802Swiss-Prot
Residues / weight
638 residues · 65,044 Da
Also known as
2.3.1.12 · Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex · E2

Resolves to

Protein
UniProtP10802UniProt nameODP2_AZOVI
Gene
GenBank580740
Structure
PDB1DPBPDB1DPCPDB1DPD
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, and which indications are they being tested in?

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