DB01992InvestigationalNutraceuticalSmall molecule
Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, well known for it's role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric... All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it, or a thioester form of it, as a substrate.
- Mechanism
- Curator reviewed
Pharmacologically active on Carnitine O-acetyltransferase
- Formula / weight
- C21H36N7O16P3S · 767.534 g/mol (avg)
- Also known as
- CoA-SH · CoASH · HSCoA
Resolves to
Clinical / RWD
Structure
InChIKey
RGJOEKWQDUBAIZ-IBOSZNHHSA-NSMILESCC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCSWhat you can answer from here — as of September 12, 2026
Which drugs share a target with Coenzyme A, and which of those have an active Phase 3 trial?
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