Formyl-CoA:oxalate CoA-transferase

BE0001310ProteinOxalobacter formigenesfrc

Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). It is acted on by 2 drugs in DrugBank.

Gene name
frc
UniProtKB entry
O06644Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
428 residues · 47,327 Da
Also known as
2.8.3.16 · FCOCT · Formyl-coenzyme A transferase

Resolves to

Protein
UniProtO06644UniProt nameFCTA_OXAFO
Gene
GenBank2102704
Structure
PDB1P5HPDB1P5RPDB1T3Z
Drugs

What you can answer from here — as of September 04, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Formyl-CoA:oxalate CoA-transferase, and which indications are they being tested in?

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