L-lactate dehydrogenase

BE0001324ProteinThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)ldh

Catalyzes the conversion of lactate to pyruvate. It is acted on by 2 drugs in DrugBank.

Gene name
ldh
UniProtKB entry
P16115Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
319 residues · 34,994 Da
Also known as
1.1.1.27 · L-LDH

Resolves to

Protein
UniProtP16115UniProt nameLDH_THEMA
Gene
NCBI Gene897800GenBank396281
Pharmacology
KEGGtma:TM1867
Structure
PDB1A5Z
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on L-lactate dehydrogenase, how selective are they, and which programs against it are still in active trials?

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