Putrescine-binding periplasmic protein PotF

BE0001328ProteinEscherichia coli (strain K12)potF

Part of the ABC transporter complex PotFGHI involved in putrescine uptake (PubMed:23719730, PubMed:8416922). It is acted on by 1 drug in DrugBank.

Gene name
potF
UniProtKB entry
P31133Swiss-Prot
Cellular location
Periplasm
Residues / weight
370 residues · 40,839 Da
Also known as
Putrescine-binding periplasmic protein · Putrescine-binding periplasmic protein precursor

Resolves to

Protein
UniProtP31133UniProt namePOTF_ECOLI
Gene
NCBI Gene945480GenBank147334
Pharmacology
KEGGecj:JW0838
Structure
PDB1A99PDB4JDF
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Putrescine-binding periplasmic protein PotF, and which indications are they being tested in?

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