Putrescine

DB01917InvestigationalSmall molecule

Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines. These are compounds containing more... Known drug targets of putrescine include putrescine-binding periplasmic protein, ornithine decarboxylase, and S-adenosylmethionine decarboxylase proenzyme.

Chemical structure of Putrescine
Mechanism
Curator reviewed
Formula / weight
C4H12N2 · 88.1515 g/mol (avg)
Also known as
1,4-Diaminobutane
Code names
NSC-60545

Resolves to

Compound
UNIIV10TVZ52E4CAS110-60-1ChEMBLCHEMBL46257ChEBI17148PubChem1045KEGGC02896
Structure
InChIKeyKIDHWZJUCRJVML-UHFFFAOYSA-NSMILESNCCCCN
Targets
P11926ODC1P17707AMD1P08588ADRB1P07550ADRB2P31133potF
Transporters
Q9H015SLC22A4

What you can answer from here — as of September 23, 2026

5Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1TransporterSubstrate / inhibitor direction, not just membership
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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8+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Putrescine, and which of those have an active Phase 3 trial?

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