Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase

BE0001402ProteinVACVOPG102

Displays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities. It is acted on by 8 drugs in DrugBank.

Gene name
OPG102
UniProtKB entry
P07617Swiss-Prot
Cellular location
Virion
Residues / weight
333 residues · 38,888 Da
Also known as
2.1.1.57 · PAP-S · PAPS · Poly(A) polymerase regulatory subunit · Poly(A) polymerase small subunit

Resolves to

Protein
UniProtP07617UniProt nameMCE_VACCW
Gene
NCBI Gene3707551GenBank61396
Pharmacology
KEGGvg:3707551
Structure
PDB1AV6PDB1B42PDB1BKY
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, and which indications are they being tested in?

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