S-adenosyl-L-homocysteine

DB01752ExperimentalSmall molecule

5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.

Chemical structure of S-adenosyl-L-homocysteine
Formula / weight
C14H20N6O5S · 384.411 g/mol (avg)
Also known as
Adenosyl-L-homocysteine · adenosylhomocysteine · AdoHcy · S-Adenosylhomocysteine

Resolves to

Compound
UNII8K31Q2S66SCAS979-92-0ChEMBLCHEMBL418052ChEBI57856PubChem439155KEGGC00021
Structure
InChIKeyZJUKTBDSGOFHSH-WFMPWKQPSA-NSMILESN[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12)C(O)=O
Targets
Q9UBC3DNMT3BP50135HNMTP07617OPG102O87696cbiFP22061PCMT1P12823Genome polyproteinP11086PNMTP9WPB5cmaA2+29 more

What you can answer from here — as of September 23, 2026

37Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
41+ReferencesStructured and connected to the statements they support
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Which drugs share a target with S-adenosyl-L-homocysteine, and which of those have an active Phase 3 trial?

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