Galactoside O-acetyltransferase

BE0001404ProteinEscherichia coli (strain K12)lacA

Catalyzes the CoA-dependent transfer of an acetyl group to the 6-O-methyl position of a range of galactosides, glucosides, and lactosides (PubMed:14009486, PubMed:4630409, PubMed:7592843). It is acted on by 3 drugs in DrugBank.

Gene name
lacA
UniProtKB entry
P07464Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
203 residues · 22,799 Da
Also known as
2.3.1.18 · Acetyl-CoA:galactoside 6-O-acetyltransferase · GAT · Thiogalactoside acetyltransferase · Thiogalactoside transacetylase

Resolves to

Protein
UniProtP07464UniProt nameTHGA_ECOLI
Gene
NCBI Gene945674GenBank551814
Pharmacology
KEGGecj:JW0333
Structure
PDB1KQAPDB1KRRPDB1KRU
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Galactoside O-acetyltransferase, and which indications are they being tested in?

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