Isopentenyl-diphosphate Delta-isomerase

BE0001417ProteinEscherichia coli (strain K12)idi

Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). It is acted on by 5 drugs in DrugBank.

Gene name
idi
UniProtKB entry
Q46822Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
182 residues · 20,508 Da
Also known as
5.3.3.2 · IPP isomerase · IPP:DMAPP isomerase · Isopentenyl pyrophosphate isomerase · ygfV

Resolves to

Protein
UniProtQ46822UniProt nameIDI_ECOLI
Gene
NCBI Gene949020GenBank4633513
Pharmacology
KEGGecj:JW2857
Structure
PDB1HX3PDB1HZTPDB1I9A
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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22+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Isopentenyl-diphosphate Delta-isomerase, and which indications are they being tested in?

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