Beta-lactamase

BE0001430ProteinEnterobacter cloacaeampC

This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. It is acted on by 13 drugs in DrugBank.

Gene name
ampC
UniProtKB entry
P05364Swiss-Prot
Cellular location
Periplasm
Residues / weight
381 residues · 41,301 Da
Also known as
3.5.2.6 · Cephalosporinase

Resolves to

Protein
UniProtP05364UniProt nameAMPC_ENTCL
Gene
GenBank42261
Structure
PDB1BLSPDB1GCEPDB1RGZ
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Beta-lactamase, how selective are they, and which programs against it are still in active trials?

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