Glucose-6-phosphate 1-dehydrogenase

BE0001439ProteinLeuconostoc mesenteroideszwf

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone. It is acted on by 3 drugs in DrugBank.

Gene name
zwf
UniProtKB entry
P11411Swiss-Prot
Residues / weight
486 residues · 54,441 Da
Also known as
1.1.1.363 · 1.1.1.49 · G6PD · Glucose-6-phosphate dehydrogenase (NAD(P)(+))

Resolves to

Protein
UniProtP11411UniProt nameG6PD_LEUME
Gene
GenBank149631
Pharmacology
KEGGag:AAA25265
Structure
PDB1DPGPDB1E77PDB1E7M
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glucose-6-phosphate 1-dehydrogenase, and which indications are they being tested in?

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