Dimethyl sulfoxide/trimethylamine N-oxide reductase

BE0001485ProteinRhodobacter sphaeroidesdmsA

Catalyzes the reduction of dimethyl sulfoxide (DMSO) and trimethylamine N-oxide (TMAO) to dimethyl sulfide (DMS) and trimethylamine, respectively. It is acted on by 2 drugs in DrugBank.

Gene name
dmsA
UniProtKB entry
Q57366Swiss-Prot
Cellular location
Periplasm
Residues / weight
822 residues · 89,207 Da
Also known as
1.7.2.3 · DMSO reductase · dsrA

Resolves to

Protein
UniProtQ57366UniProt nameDSTOR_CERSP
Gene
GenBank1161236
Structure
PDB1EU1
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Dimethyl sulfoxide/trimethylamine N-oxide reductase, and which indications are they being tested in?

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