Cysteine desulfurase

BE0001511ProteinEscherichia coli (strain K12)sufS

Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. It is acted on by 5 drugs in DrugBank.

Gene name
sufS
UniProtKB entry
P77444Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
406 residues · 44,433 Da
Also known as
2.8.1.7 · CSD · csdB · Cysteine sulfinate desulfinase · SCL

Resolves to

Pharmacology

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cysteine desulfurase, how selective are they, and which programs against it are still in active trials?

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