Glycine oxidase

BE0001590ProteinBacillus subtilis (strain 168)thiO

Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha-keto acids, ammonia/amine, and hydrogen peroxide. It is acted on by 2 drugs in DrugBank.

Gene name
thiO
UniProtKB entry
O31616Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
369 residues · 40,937 Da
Also known as
1.4.3.19 · GO · goxB · yjbR

Resolves to

Protein
UniProtO31616UniProt nameGLYOX_BACSU
Gene
NCBI Gene939377GenBank2633520
Pharmacology
KEGGbsu:BSU11670
Structure
PDB1NG3PDB1NG4PDB1RYI
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glycine oxidase, how selective are they, and which programs against it are still in active trials?

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