Methylmalonyl-CoA carboxyltransferase 5S subunit

BE0001641ProteinPropionibacterium freudenreichii subsp. shermanii

The 5S subunit specifically catalyzes the transfer of the carboxyl group from biotin of the 1.3S subunit to pyruvate to form oxaloacetate and 1.3S biotin. It is acted on by 3 drugs in DrugBank.

UniProtKB entry
Q70AC7Swiss-Prot
Residues / weight
505 residues · 55,649 Da
Also known as
2.1.3.1 · Transcarboxylase 5S subunit

Resolves to

Protein
UniProtQ70AC7UniProt name5S_PROFR
Gene
GenBank38304072
Structure
PDB1RQBPDB1RQEPDB1RQH
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Methylmalonyl-CoA carboxyltransferase 5S subunit, and which indications are they being tested in?

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