L-carnitine CoA-transferase

BE0001666ProteinEscherichia coli (strain K12)caiB

Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. It is acted on by 2 drugs in DrugBank.

Gene name
caiB
UniProtKB entry
P31572Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
405 residues · 45,126 Da
Also known as
2.8.3.21 · Crotonobetainyl-CoA:carnitine CoA-transferase · yaaN

Resolves to

Protein
UniProtP31572UniProt nameCAIB_ECOLI
Gene
NCBI Gene948997GenBank495242
Pharmacology
KEGGecj:JW0037
Structure
PDB1XA3PDB1XA4PDB1XK6
Drugs

What you can answer from here — as of September 04, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on L-carnitine CoA-transferase, and which indications are they being tested in?

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