Aspartate-semialdehyde dehydrogenase

BE0001681ProteinHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)asd

Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate. It is acted on by 3 drugs in DrugBank.

Gene name
asd
UniProtKB entry
P44801Swiss-Prot
Residues / weight
371 residues · 40,539 Da
Also known as
1.2.1.11 · ASA dehydrogenase · Aspartate-beta-semialdehyde dehydrogenase

Resolves to

Protein
UniProtP44801UniProt nameDHAS_HAEIN
Gene
NCBI Gene949960GenBank1573644
Pharmacology
KEGGhin:HI0646
Structure
PDB1NWCPDB1NWHPDB1NX6
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Aspartate-semialdehyde dehydrogenase, and which indications are they being tested in?

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