M-phase inducer phosphatase 2

BE0001705ProteinHumansCDC25B

Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression (PubMed:1836978, PubMed:20360007). It is acted on by 4 drugs in DrugBank.

Gene name
CDC25B
UniProtKB entry
P30305Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Residues / weight
580 residues · 64,987 Da
Also known as
3.1.3.48 · CDC25HU2 · Dual specificity phosphatase Cdc25B

Resolves to

Protein
UniProtP30305UniProt nameMPIP2_HUMAN
Gene
HGNCHGNC:1726NCBI Gene994GenBank180173GeneCardsCDC25B
Pharmacology
KEGGhsa:994
Structure
PDB1CWRPDB1CWSPDB1CWT
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which compounds in development act on M-phase inducer phosphatase 2, and which indications are they being tested in?

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