Ras-related protein Rab-9A

BE0001710ProteinHumansRAB9A

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. It is acted on by 2 drugs in DrugBank.

Gene name
RAB9A
UniProtKB entry
P51151Swiss-Prot
Cellular location
Cell membrane
Residues / weight
201 residues · 22,837 Da
Also known as
3.6.5.2 · RAB9

Resolves to

Protein
UniProtP51151UniProt nameRAB9A_HUMAN
Gene
HGNCHGNC:9792NCBI Gene9367GenBank1174147GeneCardsRAB9A
Pharmacology
KEGGhsa:9367
Structure
PDB1WMSPDB7E1T
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Ras-related protein Rab-9A, how selective are they, and which programs against it are still in active trials?

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