Type IV major pilin protein PilE1

BE0001713ProteinNeisseria gonorrhoeaepilE1

Major component of the type IV pilus (T4P) that plays a role in cellular adherence, microcolony formation, resistance to neutrophil mediated killing, twitching motility as well as transformation (PubMed:27213957). It is acted on by 3 drugs in DrugBank.

Gene name
pilE1
UniProtKB entry
P02974Swiss-Prot
Cellular location
Fimbrium
Residues / weight
165 residues · 17,944 Da
Also known as
Fimbrial protein · MS11 antigen · Pilin

Resolves to

Protein
UniProtP02974UniProt nameFMM1_NEIGO
Gene
GenBank150288
Structure
PDB1AY2PDB2HI2PDB2HIL
Drugs

What you can answer from here — as of May 03, 2025

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
2GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
16+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Type IV major pilin protein PilE1, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In