Elongation factor Tu-B

BE0001735ProteinThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)tufB

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. It is acted on by 2 drugs in DrugBank.

Gene name
tufB
UniProtKB entry
P60339Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
406 residues · 44,782 Da
Also known as
3.6.5.3 · EF-Tu-B

Resolves to

Protein
UniProtP60339UniProt nameEFTU2_THET8
Gene
NCBI Gene3168327GenBank312960
Pharmacology
KEGGttj:TTHA0251
Structure
PDB2C77PDB2P8WPDB2P8X
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Elongation factor Tu-B, and which indications are they being tested in?

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