Phosphopantetheine adenylyltransferase

BE0001757ProteinShigella flexnericoaD

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. It is acted on by 3 drugs in DrugBank.

Gene name
coaD
UniProtKB entry
P0A6I8Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
159 residues · 17,837 Da
Also known as
2.7.7.3 · Dephospho-CoA pyrophosphorylase · kdtB · Pantetheine-phosphate adenylyltransferase · PPAT

Resolves to

Protein
UniProtP0A6I8UniProt nameCOAD_SHIFL
Gene
NCBI Gene1026203GenBank24054145
Pharmacology
KEGGsfl:SF3673
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Phosphopantetheine adenylyltransferase, and which indications are they being tested in?

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