Autolysin

BE0001790ProteinStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)lytA

Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. It is acted on by 3 drugs in DrugBank.

Gene name
lytA
UniProtKB entry
P06653Swiss-Prot
Cellular location
Secreted
Residues / weight
318 residues · 36,544 Da
Also known as
3.5.1.28 · Cell wall hydrolase · Mucopeptide aminohydrolase · Murein hydrolase · N-acetylmuramoyl-L-alanine amidase

Resolves to

Protein
UniProtP06653UniProt nameALYS_STRPN
Gene
GenBank153695
Pharmacology
KEGGspn:SP_1937
Structure
PDB1GVMPDB1H8GPDB1HCX
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
6GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
7+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Autolysin, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In