Chloramphenicol acetyltransferase
Details
- Name
- Chloramphenicol acetyltransferase
- Kind
- protein
- Synonyms
- 2.3.1.28
- CAT
- Gene Name
- cat
- UniProtKB Entry
- P62580Swiss-Prot
- Organism
- Salmonella typhi
- NCBI Taxonomy ID
- 90370
- Amino acid sequence
>lcl|BSEQ0016565|Chloramphenicol acetyltransferase MEKKITGYTTVDISQWHRKEHFEAFQSVAQCTYNQTVQLDITAFLKTVKKNKHKFYPAFI HILARLMNAHPEFRMAMKDGELVIWDSVHPCYTVFHEQTETFSSLWSEYHDDFRQFLHIY SQDVACYGENLAYFPKGFIENMFFVSANPWVSFTSFDLNVANMDNFFAPVFTMGKYYTQG DKVLMPLAIQVHHAVCDGFHVGRMLNELQQYCDEWQGGA
- Number of residues
- 219
- Molecular Weight
- 25663.08
- Theoretical pI
- 6.36
- GO Classification
- Functionschloramphenicol O-acetyltransferase activityProcessesresponse to antibiotic
- General Function
- This enzyme is an effector of chloramphenicol resistance in bacteria.
- Specific Function
- chloramphenicol O-acetyltransferase activity
- Pfam Domain Function
- CAT (PF00302)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0016566|Chloramphenicol acetyltransferase (cat) ATGGAGAAAAAAATCACTGGATATACCACCGTTGATATATCCCAATGGCATCGTAAAGAA CATTTTGAGGCATTTCAGTCAGTTGCTCAATGTACCTATAACCAGACCGTTCAGCTGGAT ATTACGGCCTTTTTAAAGACCGTAAAGAAAAATAAGCACAAGTTTTATCCGGCCTTTATT CACATTCTTGCCCGCCTGATGAATGCTCATCCGGAATTCCGTATGGCAATGAAAGACGGT GAGCTGGTGATATGGGATAGTGTTCACCCTTGTTACACCGTTTTCCATGAGCAAACTGAA ACGTTTTCATCGCTCTGGAGTGAATACCACGACGATTTCCGGCAGTTTCTACACATATAT TCGCAAGATGTGGCGTGTTACGGTGAAAACCTGGCCTATTTCCCTAAAGGGTTTATTGAG AATATGTTTTTCGTCTCAGCCAATCCCTGGGTGAGTTTCACCAGTTTTGATTTAAACGTG GCCAATATGGACAACTTCTTCGCCCCCGTTTTCACCATGGGCAAATATTATACGCAAGGC GACAAGGTGCTGATGCCGCTGGCGATTCAGGTTCATCATGCCGTTTGTGATGGCTTCCAT GTCGGCAGAATGCTTAATGAATTACAACAGTACTGCGATGAGTGGCAGGGCGGGGCGTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P62580 UniProtKB Entry Name CAT_SALTI GenBank Protein ID 16505914 GenBank Gene ID AL513383 KEGG ID sty:HCM1.206 NCBI Gene ID 1251342 - General References
- Parkhill J, Dougan G, James KD, Thomson NR, Pickard D, Wain J, Churcher C, Mungall KL, Bentley SD, Holden MT, Sebaihia M, Baker S, Basham D, Brooks K, Chillingworth T, Connerton P, Cronin A, Davis P, Davies RM, Dowd L, White N, Farrar J, Feltwell T, Hamlin N, Haque A, Hien TT, Holroyd S, Jagels K, Krogh A, Larsen TS, Leather S, Moule S, O'Gaora P, Parry C, Quail M, Rutherford K, Simmonds M, Skelton J, Stevens K, Whitehead S, Barrell BG: Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18. Nature. 2001 Oct 25;413(6858):848-52. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Fusidic acid approved, investigational unknown target inhibitor Details