Fusidic acid is a topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. An antibiotic isolated from the fermentation broth of Fusidium coccineum.
- Mechanism
- Curator reviewed
Fusidic acid works by interfering with bacterial protein synthesis, specifically by preventing the translocation of the elongation factor G (EF-G) from the ribosome. It also can inhibit chloramphenicol acetyltransferase enzymes.
- Primary indication
- For the treatment of bacterial infections.Curator reviewed · 19 structured indications
- Formula / weight
- C31H48O6 · 516.7092 g/mol (avg)
- First approval
- Canada, 1998
- Also known as
- Fucidate · Fucidin acid · Fusidate · Fusidine · Ramycin
- Code names
- NSC-56192 · SQ-16603
- Brand names
Resolves to
Structure
InChIKey
IECPWNUMDGFDKC-MZJAQBGESA-NSMILES[H][C@@]12C[C@@H](O)[C@@]3([H])[C@@]4(C)CC[C@@H](O)[C@@H](C)[C@]4([H])CC[C@]3(C)[C@@]1(C)C[C@H](OC(C)=O)\C2=C(\CCC=C(C)C)C(O)=OTransporters
What you can answer from here — as of September 23, 2026
3Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
4TransportersSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Fusidic acid, and which of those have an active Phase 3 trial?
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