Cell division protein FtsZ

BE0001813ProteinThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)ftsZ

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. It is acted on by 2 drugs in DrugBank.

Gene name: ftsZ
UniProtKB entry: O08398Swiss-Prot
Cellular location: Cytoplasm
Residues / weight: 351 residues · 38,307 Da

Resolves to

Protein

UniProtO08398UniProt nameFTSZ_THEMA

Gene

NCBI Gene898507GenBank2104497

Pharmacology

KEGGtma:TM0836

Structure

PDB1W5FPDB4A2A

Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action

7GO termsFunction, process and component, as structured annotations

2Pfam domainsDomain architecture mapped to Pfam families and clans

7+ReferencesStructured and connected to the statements they support

Which approved drugs act on Cell division protein FtsZ, how selective are they, and which programs against it are still in active trials?

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