Deacetoxycephalosporin C synthase

BE0001833ProteinStreptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602)cefE

Catalyzes the step from penicillin N to deacetoxy-cephalosporin C. It is acted on by 3 drugs in DrugBank.

Gene name
cefE
UniProtKB entry
P18548Swiss-Prot
Residues / weight
311 residues · 34,555 Da
Also known as
1.14.20.1 · DAOCS · Expandase

Resolves to

Protein
UniProtP18548UniProt nameCEFE_STRCL
Gene
GenBank153205
Structure
PDB1DCSPDB1E5HPDB1E5I
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Deacetoxycephalosporin C synthase, and which indications are they being tested in?

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