Diaminopimelate decarboxylase

BE0001844ProteinEscherichia coli (strain K12)lysA

Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. It is acted on by 2 drugs in DrugBank.

Gene name
lysA
UniProtKB entry
P00861Swiss-Prot
Residues / weight
420 residues · 46,177 Da
Also known as
4.1.1.20 · DAP decarboxylase

Resolves to

Protein
UniProtP00861UniProt nameDCDA_ECOLI
Gene
NCBI Gene947313GenBank455170
Pharmacology
KEGGecj:JW2806
Structure
PDB1KNWPDB1KO0
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Diaminopimelate decarboxylase, and which indications are they being tested in?

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