GTPase Der

BE0001848ProteinThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)der

GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
der
UniProtKB entry
Q9X1F8Swiss-Prot
Residues / weight
439 residues · 50,014 Da
Also known as
engA · GTP-binding protein EngA · TmDer

Resolves to

Protein
UniProtQ9X1F8UniProt nameDER_THEMA
Gene
NCBI Gene898030GenBank4982010
Pharmacology
KEGGtma:TM1446
Structure
PDB1MKY
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on GTPase Der, and which indications are they being tested in?

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