3-hydroxy-3-methylglutaryl-coenzyme A reductase

BE0001856ProteinPseudomonas mevaloniimvaA

P.mevalonii can use mevalonate as sole carbon source. It is acted on by 4 drugs in DrugBank.

Gene name
mvaA
UniProtKB entry
P13702Swiss-Prot
Residues / weight
428 residues · 45,590 Da
Also known as
1.1.1.88 · HMG-CoA reductase

Resolves to

Protein
UniProtP13702UniProt nameMVAA_PSEMV
Gene
GenBank151259
Structure
PDB1QAXPDB1QAYPDB1R31
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 3-hydroxy-3-methylglutaryl-coenzyme A reductase, and which indications are they being tested in?

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