Quinohemoprotein alcohol dehydrogenase

BE0001870ProteinComamonas testosteroniqheDH

Catalyzes the dye-linked oxidation of primary alcohols to the corresponding aldehydes and the (subsequent) oxidation of the aldehydes to carboxylic acids. It is acted on by 4 drugs in DrugBank.

Gene name
qheDH
UniProtKB entry
Q46444Swiss-Prot
Cellular location
Periplasm
Residues / weight
708 residues · 76,822 Da
Also known as
1.1.9.1 · Alcohol dehydrogenase (azurin) · PQQ-containing alcohol dehydrogenase · PQQ-dependent ADH · QH-ADH

Resolves to

Protein
UniProtQ46444UniProt nameQHED_COMTE
Gene
GenBank663196
Structure
PDB1KB0
Drugs

What you can answer from here — as of May 03, 2025

4DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Quinohemoprotein alcohol dehydrogenase, and which indications are they being tested in?

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