Alkaline phosphatase

BE0001896ProteinEscherichia coli (strain K12)phoA

Alkaline phosphatase (Escherichia coli (strain K12)) is a protein target in DrugBank. It is acted on by 5 drugs in DrugBank.

Gene name
phoA
UniProtKB entry
P00634Swiss-Prot
Cellular location
Periplasm
Residues / weight
471 residues · 49,438 Da
Also known as
3.1.3.1 · APase

Resolves to

Protein
UniProtP00634UniProt namePPB_ECOLI
Gene
NCBI Gene945041GenBank581187
Pharmacology
KEGGecj:JW0374
Structure
PDB1AJAPDB1AJBPDB1AJC
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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30+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Alkaline phosphatase, how selective are they, and which programs against it are still in active trials?

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