Mannan endo-1,4-beta-mannosidase

BE0001911ProteinCellvibrio japonicus (strain Ueda107)manA

Catalyzes the endo hydrolysis of beta-1,4-linked mannan and galactomannan, but displays little activity towards other polysaccharides located in the plant cell wall (PubMed:11382747). It is acted on by 5 drugs in DrugBank.

Gene name
manA
UniProtKB entry
P49424Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
423 residues · 47,487 Da
Also known as
3.2.1.78 · man26A · ManA · Mannanase 26A · Mannanase A

Resolves to

Protein
UniProtP49424UniProt nameMANA_CELJU
Gene
GenBank14594858
Pharmacology
KEGGcja:CJA_2770
Structure
PDB1GVYPDB1GW1PDB1J9Y
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Mannan endo-1,4-beta-mannosidase, and which indications are they being tested in?

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