Fumarate hydratase class II

BE0001914ProteinEscherichia coli (strain K12)fumC

Involved in the TCA cycle. It is acted on by 4 drugs in DrugBank.

Gene name
fumC
UniProtKB entry
P05042Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
467 residues · 50,488 Da
Also known as
4.2.1.2 · Aerobic fumarase · Fumarase C · Iron-independent fumarase

Resolves to

Protein
UniProtP05042UniProt nameFUMC_ECOLI
Gene
NCBI Gene946147GenBank41513
Pharmacology
KEGGecj:JW1603
Structure
PDB1FUOPDB1FUPPDB1FUQ
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Fumarate hydratase class II, how selective are they, and which programs against it are still in active trials?

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