Deoxyribodipyrimidine photo-lyase

BE0001969ProteinThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)phr

Involved in repair of UV radiation-induced DNA damage. It is acted on by 2 drugs in DrugBank.

Gene name
phr
UniProtKB entry
P61497Swiss-Prot
Residues / weight
420 residues · 47,900 Da
Also known as
4.1.99.3 · DNA photolyase · Photoreactivating enzyme

Resolves to

Protein
UniProtP61497UniProt namePHR_THET8
Gene
NCBI Gene3169528GenBank15080709
Pharmacology
KEGGttj:TTHB102
Structure
PDB1IQRPDB1IQUPDB2J07
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Deoxyribodipyrimidine photo-lyase, how selective are they, and which programs against it are still in active trials?

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