Anti-sigma F factor antagonist

BE0001975ProteinLysinibacillus sphaericusspoIIAA

In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition. It is acted on by 1 drug in DrugBank.

Gene name
spoIIAA
UniProtKB entry
O32723Swiss-Prot
Residues / weight
117 residues · 13,043 Da
Also known as
Stage II sporulation protein AA

Resolves to

Protein
UniProtO32723UniProt nameSP2AA_LYSSH
Gene
GenBank2529269
Structure
PDB1H4XPDB1H4YPDB1H4Z
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
2GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
4+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Anti-sigma F factor antagonist, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In