Protein-methionine-sulfoxide reductase catalytic subunit MsrP

BE0001990ProteinEscherichia coli O157:H7msrP

Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. It is acted on by 1 drug in DrugBank.

Gene name
msrP
UniProtKB entry
Q8XB74Swiss-Prot
Cellular location
Periplasm
Residues / weight
334 residues · 37,357 Da
Also known as
1.8.-.- · 1.8.5.- · Sulfoxide reductase catalytic subunit YedY

Resolves to

Protein
UniProtQ8XB74UniProt nameMSRP_ECO57
Gene
NCBI Gene912771GenBank12516082
Pharmacology
KEGGece:Z3063
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Protein-methionine-sulfoxide reductase catalytic subunit MsrP, how selective are they, and which programs against it are still in active trials?

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