7alpha-hydroxysteroid dehydrogenase

BE0001999ProteinEscherichia coli (strain K12)hdhA

7alpha-hydroxysteroid dehydrogenase involved in the metabolism of bile acids. It is acted on by 2 drugs in DrugBank.

Gene name
hdhA
UniProtKB entry
P0AET8Swiss-Prot
Residues / weight
255 residues · 26,778 Da
Also known as
1.1.1.159 · 7-alpha-HSDH · 7-alpha-hydroxysteroid dehydrogenase · 7alpha-HSDH · hsdH

Resolves to

Protein
UniProtP0AET8UniProt nameHDHA_ECOLI
Gene
NCBI Gene946151GenBank912437
Pharmacology
KEGGecj:JW1611
Structure
PDB1AHHPDB1AHIPDB1FMC
Drugs

What you can answer from here — as of May 03, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 7alpha-hydroxysteroid dehydrogenase, and which indications are they being tested in?

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