Taurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile. As a medication, taurochenodeoxycholic... As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to increase bile...
- Mechanism
- Curator reviewed
Chenodeoxycholic acid is a primary bile acid in the liver that combines with taurine to form the bile acid taurochenodeoxycholic acid. In the bile, taurochenodeoxycholic acid is either a sodium (most) or potassium salt. Taurochenodeoxycholic acid is normally produced in the liver, and its physiologic function as a bile salt is to emulsify lipids such as cholesterol in the bile. As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to increase bile discharge into the duodenum. The mechanism of action of taurochenodeoxycholic acid in inflammation and cancer has yet to be determined.
- Primary indication
- Taurochenodeoxycholic acid is likely indicated as a choleretic and cholagogue.Curator reviewed
- Formula / weight
- C26H45NO6S · 499.704 g/mol (avg)
- Also known as
- Chenodeoxycholoyltaurine · Taurine chenodeoxycholate · Taurochenodeoxycholate
Resolves to
BHTRKEVKTKCXOH-BJLOMENOSA-NSMILES[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)NCCS(O)(=O)=OWhat you can answer from here — as of September 01, 2026
Which companies are running trials of Taurochenodeoxycholic acid, in which indications and phases, and which of those programs are still active?
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