Dihydroorotate dehydrogenase A (fumarate)

BE0002008ProteinLactococcus lactis subsp. cremorispyrDA

Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. It is acted on by 2 drugs in DrugBank.

Gene name
pyrDA
UniProtKB entry
Q53ZE5Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
311 residues · 34,210 Da
Also known as
1.3.98.1 · DHOD A

Resolves to

Protein
UniProtQ53ZE5UniProt namePYRDA_LACLC
Gene
GenBank33302311
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
4+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Dihydroorotate dehydrogenase A (fumarate), how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In