Flavin mononucleotide is a form of vitamin B2 used to restore riboflavin in anemia, migraine, alcoholism, and hyperhomocysteinemia. Flavin mononucleotide (FMN), also known as riboflavin 5'-phosphate, is one of the two major coenzymes derived from riboflavin (vitamin B2) and is one of the principal forms in which dietary riboflavin is found.
- Mechanism
- Curator reviewed · 4 references
Flavin mononucleotide (FMN) is a precursor to flavin adenine dinucleotide (FAD) which is involved in metabolic redox reactions critical to a variety of functions, including ATP production, DNA repair, apoptosis, and protein folding. Administered systemically, FMN serves to supplement endogenous supply in patients who may otherwise be deficient.
For its indicated use in corneal collagen cross-linking, FMN acts as a photoenhancer. When used with a system delivering UV-A light, FMN generates singlet oxygen which is responsible for inducing the formation of cross-links within the corneal collagen.
- Primary indication
- Administered systemically, flavin mononucleotide is primarily indicated for the treatment of riboflavin deficiency in a variety of contexts (e.g. anemia).Curator reviewed · 6 structured indications
- Formula / weight
- C17H21N4O9P · 456.3438 g/mol (avg)
- First approval
- Canada, 1998 · United States, 2001
- Also known as
- riboflavin 5'-phosphate · Riboflavin monophosphate · Riboflavin phosphate · riboflavine dihydrogen phosphate · Vitamin B2 (riboflavin-5-phosphate)
- Brand names
Resolves to
FVTCRASFADXXNN-SCRDCRAPSA-NSMILESCC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2What you can answer from here — as of September 12, 2026
Which drugs share a target with Flavin mononucleotide, and which of those have an active Phase 3 trial?
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