DNA-binding transcriptional dual regulator CRP

BE0002013ProteinEscherichia coli (strain K12)crp

A global transcription regulator, which plays a major role in carbon catabolite repression (CCR) as well as other processes. It is acted on by 1 drug in DrugBank.

Gene name
crp
UniProtKB entry
P0ACJ8Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
210 residues · 23,640 Da
Also known as
cAMP receptor protein · cAMP regulatory protein · cAMP-activated global transcriptional regulator CRP · cap · Catabolite activator protein

Resolves to

Protein
UniProtP0ACJ8UniProt nameCRP_ECOLI
Gene
NCBI Gene947867GenBank145594
Pharmacology
KEGGecj:JW5702
Structure
PDB1CGPPDB1G6NPDB1HW5
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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43+ReferencesStructured and connected to the statements they support
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Which compounds in development act on DNA-binding transcriptional dual regulator CRP, and which indications are they being tested in?

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