Spermidine/putrescine-binding periplasmic protein

BE0002032ProteinEscherichia coli (strain K12)potD

Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. It is acted on by 1 drug in DrugBank.

Gene name
potD
UniProtKB entry
P0AFK9Swiss-Prot
Cellular location
Periplasm
Residues / weight
348 residues · 38,867 Da
Also known as
SPBP

Resolves to

Protein
UniProtP0AFK9UniProt namePOTD_ECOLI
Gene
NCBI Gene945682
Pharmacology
KEGGecj:JW1109
Structure
PDB1POTPDB1POY
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Spermidine/putrescine-binding periplasmic protein, and which indications are they being tested in?

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