Glyceraldehyde-3-phosphate dehydrogenase A

BE0002057ProteinEscherichia coli (strain K12)gapA

Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. It is acted on by 2 drugs in DrugBank.

Gene name
gapA
UniProtKB entry
P0A9B2Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
331 residues · 35,532 Da
Also known as
1.2.1.12 · GAPDH-A · NAD-dependent glyceraldehyde-3-phosphate dehydrogenase

Resolves to

Protein
UniProtP0A9B2UniProt nameG3P1_ECOLI
Gene
NCBI Gene947679
Pharmacology
KEGGecj:JW1768
Structure
PDB1DC3PDB1DC4PDB1DC5
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glyceraldehyde-3-phosphate dehydrogenase A, and which indications are they being tested in?

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