Thiol:disulfide interchange protein DsbC

BE0002075ProteinEscherichia coli (strain K12)dsbC

Acts as a disulfide isomerase, interacting with incorrectly folded proteins to correct non-native disulfide bonds. It is acted on by 1 drug in DrugBank.

Gene name: dsbC
UniProtKB entry: P0AEG6Swiss-Prot
Cellular location: Periplasm
Residues / weight: 236 residues · 25,621 Da
Also known as: xprA

Resolves to

Protein

UniProtP0AEG6UniProt nameDSBC_ECOLI

Gene

NCBI Gene947363

Pharmacology

KEGGecj:JW2861

Structure

PDB1EEJPDB1G0TPDB1JZD

Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action

7GO termsFunction, process and component, as structured annotations

2Pfam domainsDomain architecture mapped to Pfam families and clans

12+ReferencesStructured and connected to the statements they support

Which compounds in development act on Thiol:disulfide interchange protein DsbC, and which indications are they being tested in?

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