Laminin subunit alpha-3

BE0002111ProteinHumansLAMA3

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is acted on by 2 drugs in DrugBank.

Gene name
LAMA3
UniProtKB entry
Q16787Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix, basement membrane
Residues / weight
3,333 residues · 366,616 Da
Also known as
E170 · Epiligrin 170 kDa subunit · Epiligrin subunit alpha · Kalinin subunit alpha · Laminin-5 subunit alpha

Resolves to

Protein
UniProtQ16787UniProt nameLAMA3_HUMAN
Gene
HGNCHGNC:6483NCBI Gene3909GenBank551597GeneCardsLAMA3
Pharmacology
KEGGhsa:3909
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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13GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Laminin subunit alpha-3, how selective are they, and which programs against it are still in active trials?

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