Protamine

DB13700ApprovedInvestigationalWithdrawnSmall moleculeHeparin Reversal Agent

Protamine is a heparin antagonist indicated in the treatment of heparin overdoses, to counteract heparins preoperatively, or during cardiac surgery and dialysis. A medication used to treat overdoses of medications that cause bleeding.

Resolves to

Compound
UNII72G3UY6T4NCAS9012-00-4
Clinical / RWD
RxNorm8826ATCV03AB14
Targets
P00734F2P08709F7P41180CASRP13726F3P20231TPSB2

What you can answer from here — as of July 17, 2026

6Protein targetsEach mapped to UniProt, with action and pharmacological action
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22Clinical trialsPhase, status and sponsor resolved per trial
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1Structured indicationCondition, population, route and combination as fields, not prose
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1ContraindicationEach with its own population and attribute set
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9Marketed productsAcross 4 countries and 5 labellers
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1ATC codeIncluding every combination product, plus 11 drug categories
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13+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Protamine, and which of those have an active Phase 3 trial?

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