Plasma serine protease inhibitor

BE0002112ProteinHumansSERPINA5

Heparin-dependent serine protease inhibitor acting in body fluids and secretions. It is acted on by 5 drugs in DrugBank.

Gene name
SERPINA5
UniProtKB entry
P05154Swiss-Prot
Cellular location
Secreted, extracellular space
Residues / weight
406 residues · 45,674 Da
Also known as
Acrosomal serine protease inhibitor · PAI-3 · PAI3 · PCI · PLANH3

Resolves to

Protein
UniProtP05154UniProt nameIPSP_HUMAN
Gene
HGNCHGNC:8723NCBI Gene5104GenBank180550GeneCardsSERPINA5
Pharmacology
KEGGhsa:5104
Structure
PDB1LQ8PDB2HI9PDB2OL2
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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49+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Plasma serine protease inhibitor, how selective are they, and which programs against it are still in active trials?

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