Protein ERGIC-53

BE0002119ProteinHumansLMAN1

Mannose-specific lectin. It is acted on by 3 drugs in DrugBank.

Gene name
LMAN1
UniProtKB entry
P49257Swiss-Prot
Cellular location
Endoplasmic reticulum-Golgi intermediate compartment membrane
Residues / weight
510 residues · 57,549 Da
Also known as
ER-Golgi intermediate compartment 53 kDa protein · ERGIC53 · F5F8D · Gp58 · Intracellular mannose-specific lectin MR60

Resolves to

Protein
UniProtP49257UniProt nameLMAN1_HUMAN
Gene
HGNCHGNC:6631NCBI Gene3998GenBank433938GeneCardsLMAN1
Pharmacology
KEGGhsa:3998
Structure
PDB3A4UPDB3LCPPDB3WHT
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Protein ERGIC-53, how selective are they, and which programs against it are still in active trials?

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